After the graduation in Organ and Composition in 1994 at the Conservatorio di Musica G. Verdi in Milan, Marcello continued his studies at the Musik Hochschule in Wien.

In 1997 he became student and assistant of Maestro Romano Gandolfi at the Toscanini Association in Parma, Italy.
He was employed as 1st Kappelmeister in Bern, Switzerland in 1999 and held this position until 2001. Here he conducted numerous performances, including Hansel and Gretel, Cosi fan Tutte, Die Fledermaus, Il Trovatore, Magic Flute, Der Fogelhaendler, Marta and various ballets and musicals. During this period he was also engaged to conduct Nabucco on tour in Germany, Un Ballo in Maschera, Rigoletto and Turandot with the choir and orchestra from Bolshoi Minsk.

In 2001 Marcello made his debut both in the USA and South Africa, with Turandot (Colorado Opera Company), Rigoletto and Mahler's 2nd Symphony (Opera of Cape Town, South Africa).

In Kyrburg and Monschau in Gemany in 2002 Marcello conducted productions of Carmen, Rigoletto and Trovatore. He also travelled to Belarus to work with the choir and orchestra of Bolshoi Minsk. He conducted this ensemble in Tosca at the Bolshoi Theatre, Minsk, and Verdi's Requiem in Besana Brianza, Italy.

During 2007 Marcello conducted, Der Freischütz and Rigoletto at The National Opera in Denmark, and symphonic concerts with Odense and Aalborg Symphony Orchestras. During this year he also conducted in Egypt with the Cairo Symphony Orchestra, Poland with Bialystok Philharmonic Orchestra and in Milano with Orchestra Teatro Carlo Coccia from Novara.

In 2008 he conducted Århus Symphony Orchestra, Denmark, and the Slovak Radio Symphony Orchestra in Bratislava. He appeared several times with Cairo Symphony Orchestra both in Cairo but also at a Gala Concert in Jordan with Placido Domingo and Julia Migenes.

From the beginning of the 2008-2009 season Marcello has been engaged as the principal conductor of the Cairo Symphony Orchestra with 21 concerts per season among these 3 tours to Italy, Germany and Denmark in 2009-10 and he debuted at the Seongnam Art Centre in Seoul, Korea, at the Royal Opera in Copenhagen with Don Carlos. The 2009 begins with concerts in Sønderborg, Denmark, with Sønderjyllands Symfoniorkester, and 10 performances of Donizetti's Elisir d'Amore in Denmark with The National Opera.